Title: Principal Investigator: Other Investigators: Institutional affiliations: I. View a list of Animal Care Manuals today. The Trusted Standard in Research, Ethics, and Compliance Training The Collaborative Institutional Training Initiative (CITI Program) is dedicated to serving the training needs of colleges and universities, healthcare institutions, technology and research organizations, and governmental agencies, as they foster integrity and professional advancement of their learners. Action is taken as per the study protocol and includes euthanizing the animal, stopping a painful procedure, or alleviating the pain or distress with other appropriate measures. The TAG or SSP will identify an ACM Coordinator to serve as the main communications conduit between the authors and AZA's Animal Welfare Committee (AWC) and Conservation, Management, & Welfare Sciences Department. The developmental processes used to compose each ACM follows a specific sequence that includes several review procedures (internal and external) before the AZA Conservation, Management, & Welfare Sciences Department reviews it and ultimately approves publication. Review high-level program plans, goals, and acceptable animal care and use procedures to remain in good standing. A clinical study uses research with human participants. Learn more about research that meets the definition human subjects research, Federal regulation requirements, and whether your project may be considered exempt. Our team is available on campus and remotely to continue the provision of services that ensure animal welfare and support the U-M research community. No animal research can be done without a strong potential for benefits to animals and/or humans. In 2018 the American Association of Feline Practitioners (AAFP) issued new safety guidelines in an effort to prevent anesthetic-related mortalities. IACUC protocols must be submitted to … For example, recommendation for linseed inclusion to diet (for improving reproduction performance or modifying milk FA) is up to 10% of DM (you can refer to Petit et al., 2010- … Animal Research Review Panel . To be on a protocol, there are several items that need to be completed. The ACM Coordinator will work with the TAG/SSP, AWC and AZA Conservation, Management, & Welfare Sciences Department to review all comments, incorporate suggestions as deemed necessary and provide a written justification report for omitting suggestions deemed unnecessary. Animal Use Protocol Texas A&M University is committed to maintaining high standards for the care and use of animals in its research, testing, and teaching programs. These interventions may be medical products, such as drugs or devices, procedures or changes to participants’ behavior, for example, diet. For example, in cancer studies, an animal might be dropped from the study and euthanised before the predetermined time point if the size of a subcutaneous tumour exceeds a specific volume . Animals, usually mice, are needed to produce these monoclonal antibody producing cells. A complete ACM Template is available to all AZA members. In the 10 years since publication, the ARRIVE guidelines have been endorsed by more than a thousand journals from across the life sciences. CO 2 must be delivered from compressed gas canister only. Generally, before experiments on animals are conducted, the research protocol must be reviewed by animal ethics committees. High quality data requires the use of procedures appropriate for the animal species used and type of data desired. b. Wildlife Laboratory Animal Use Protocol: use for wildlife field studies. intermediate animal host could be a domestic food animal, a wild animal, or a domesticated wild animal which has ... For example, at refrigeration temperature (4°C), MERS-CoV can remain viable for up to 72 hours. Evidence from animal models is referred to in the characterization of each group (IARC 2006). BACKGROUND AND SIGNIFICANCE. Drexel University. Everyone handling animals for the purpose of animal research must be listed on an IACUC protocol. animal protocols approved for this research 2. National Institutes of Health (NIH), OLAW: Animal Study Proposal Examples: Phone: (734) 763-8028 Phone: (734) 764-0277 Begin with our Project Lifecycle, D16-00072 (A3114-01), Assurance Dates: July 2017 - July 2021, 34-R-0001, Last Inspection Date: September 16, 2020. “Animal research has improved the health and welfare of animals and humans. Board-Approved Policies and Position Statements, Guidelines & Sample Documents, Programs, and Policies, Animal Program Sustainability Designations, Black-footed Ferret Recovery and Reintroduction Program Analysis, Annual Report on Conservation and Science, Resources for Greening Business Practices, Angela Peterson Excellence in Diversity Award, William G. Conway International Conservation Award, R. Marlin Perkins Award for Professional Excellence, Animal Welfare Lifetime Achievement Award, Tim O'Sullivan Award for Professional Development, The Devra Kleiman Scientific Advancement Award, Wendy Fisher Award for Professional Excellence, Zoo and Aquarium Safety: Example Practices, Free and Discounted Admissions for AZA Members. Canis lupus is a species. We will continue to use paper documents until further notice. Research is a systematic investigation to establish facts or principles, or to collect information on a subject. 2800 Plymouth Road Incorporating the information from these manuals into animal management practices at zoos and aquariums maximizes excellence in animal care and welfare, and ensures institutions are maintaining best practices. Include the following specific information, if applicable: • Animal identification methods [e.g., ear tags, tattoos, collar, cage card, implant, etc.]. For example, we can use the term gray wolf but we cannot use just Canis or lupus to describe this animal. The protocol will continue being reviewed but will remain pending approval until favourable peer reviews have been supplied. The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) are a checklist of recommendations to improve the reporting of research involving animals – maximising the quality and reliability of published research, and enabling others to better scrutinise, evaluate and reproduce it. Australian/New Zealand Standard (2010) Standard AS-NZS 2243-3:2010. IACUC/Animal Protocol. 4 Rationale 6 Procedures 8 Alternative Search 20 Procedure Relationships 21 Husbandry 22 Animal Disposition 25 Certifications 26. If you continue using our website, we'll assume that you are happy to receive all cookies on this website and you agree to our Privacy Policy. The Institutional Animal Care & Use Committee (IACUC) will begin its next round of semi-annual facility inspections on Tuesday, February 2, 2021. Animal testing, also known as animal experimentation, animal research and in vivo testing, is the use of non-human animals in experiments that seek to control the variables that affect the behavior or biological system under study.This approach can be contrasted with field studies in which animals are observed in their natural environments or habitats. This policy revises previous policy and guidelines regarding the inclusion of children in research. ACMs are considered works in progress, since practices continue to evolve through advances in scientific knowledge. In a clinical trial (also called an interventional study), participants receive specific interventions according to the research plan or protocol created by the investigators. To save time and decrease the chance of the protocol being delayed in review, the IACUC encourages people to … For a list of all ACC policies and procedures, please visit the Research & teaching with animals website. Fax: (734) 936-3235 To draft a sound scientific design of a clinical research study, the medical writer at the TGH, Office of Clinical Research recommends that the following information should be included in a research protocol. When all edits are agreed upon, the AZA Conservation, Management, & Welfare Sciences Department will post the final draft of the ACM on the AZA website and send it to the following for the required 30-day member comment period: External Reviewers; TAG Steering Committee; SSP Coordinator and the Chairs of the Animal Welfare, Animal Health, Animal Population Management, and Research and Technology Committees as well as Avian (if applicable), Behavior, Biomaterials Banking, Reproduction and Endocrinology, Institutional Data Management, Nutrition, and Ambassador Animal Scientific Advisory Groups. Please refer to the, Not sure where to start? Email: ulam-questions@umich.edu, Our team is available on campus and remotely to continue the provision of services that ensure animal welfare and support the U-M research community. A brief description of the animal activities planned for the 4 th and 5 th year of the award period should be provided in the animal protocol recognizing that the experimental details and procedures will be refined or amended at … Research protocols be submitted on the form “Application to Use Animals for Research” Teaching protocols be submitted on the form "Application to Use Animals for Teaching" Teaching protocols are reviewed for pedagogical merit. It will help facilitate the application submission process and study approval from the Office of Clinical Research and IRB. A species, by definition, is the combination of both the genus and specific epithet, not just the epithet. Writing an animal … Download the Horse ancestry submission form here. Animal Utilisation Protocol (AUP) - Research This completed Animal Utilisation Protocol (AUP) needs to be submitted to The Secretariat, Institutional Animal Care and Use Committee, c/o Unit of Ethics Research, Level 4, Office of the Deputy Vice Chancellor (Research & Innovation), Universiti Putra Malaysia, and approved by UPM IACUC prior to commencement of the animal study. Any research, testing, or teaching project which involves live vertebrate animals must be approved through the Drexel IACUC. Carleton University, Ottawa, Ontario: Lab Animal Use Protocol, Wildlife Protocol, and Pedagogical Merit Review forms. To the greatest extent possible, pre-emptive euthanasia should be advocated for any study in which an animal is likely to progress to a moribund state (impending death). For example, rather than providing two different kind of balls, provide a ball and a mirror or chew toy. In addition, the facility should be organised in a way that prevents the animals from coming into contact with disease, or with a test item other than the one under investigation. Office of Sponsored Projects & Industry Partnerships Human and Animal Regulatory Committee Office How to … Sample Research Protocol Template Published Sep 13, 2016. UW’s Office of Animal Welfare (OAW) is responsible for reviewing and approving protocols. Exclusion criteria may also reflect the ethical principles of a study in line with its humane endpoints (see Item 16. Department of Small Animal Clinical Sciences (VSCS) Texas A&M College of Veterinary Medicine & Biomedical Sciences 4474 TAMU | College Station, TX 77843-4474 Tel: 979.845.2351 | Fax: 979.845.6978 Web: vscs.tamu.edu Guideline 12 Updated February 2000 . Animal research facility The facility should be designed and operated to control selected parameters (such as temperature, humidity and light) to minimize the effects of environmental variables on the animal. For either oral or parenteral supplementation, if the underlying disease process has resolved and cobalamin body stores have been replenished, serum cobalamin concentration should be supranormal at the time of reevaluation. Amend protocols to reflect changes in … The following additional guidelines must be followed when using CO 2:. There are 3 different Animal Use Protocols to choose from depending upon the type of animal research to be conducted. The Office of Animal Welfare will be implementing the electronic system for IACUC protocol submission and review via the Kuali program shortly. Unit for Laboratory Animal Medicine (ULAM) Example of a search for alternatives for a research protocol (Word) Example of a search for alternatives for a training protocol (Word) Alternative Search Websites. Completed Animal Care Manuals include: The development of each ACM is coordinated by the AZA Animal Welfare Committee and managed by AZA's Conservation, Management, & Welfare Sciences Department. From above example, note that the classifications go from general (Animalia) to specific (C. lupus). NOT-OD-18-116: NIH Policy and Guidelines on the Inclusion of Individuals Across the Lifespan as Participants in Research Involving Human Subjects . Safety in laboratories – Microbiological Safety and Containment The following classification has been drawn up for microorganisms that are infectious for humans and animals for Australia and New Zealand by modification of the WHO guidelines and is based on the pathogenicity of the agent, the mode of … Abstract. Contact OAW for guidance on the appropriate use of animals in research.. UW’s Department of Comparative Medicine is responsible for the procurement, housing, care, and disposal of animals according to all applicable regulations.. A budget number is set up after animal use protocol approval is in place. There are six primary steps needed to complete the publication process: This site uses cookies to offer you a better browsing experience. The guiding principle of these committees is usually the 3 Rs. design portion of animal activity proposals. Find suggested parameters for a variety of tasks related to animal care and use research duties. Animal Care and Use. We no longer accept any new IACUC protocol submitted on "paper". Large animal species such as rabbits, pigs, sheep, cows, cats and ferrets: at least two different items from the species' approved enrichment database should be provided to singly housed large animals. Once completed, the AZA Conservation, Management, & Welfare Sciences Department will provide final approval and post the ACM on the AZA website accordingly. A grant proposal and an IACUC proposal have two very different purposes. Each section lists bulleted points, developed with input from AZA Committees, Scientific Advisory Groups, and the Animal Program's Population Management and Reproductive Management Centers, that are addressed by the authors. Institutional Animal Care and Use Committee Protocol Form Instructions T h efor mi s dula n c t .AC ( ) b p y Attachments may need to be completed depending on your responses to the checklist in Section V of the Core. The Institutional Animal Care and Use Committee (IACUC) and Animal Resource Center (ARC) oversee the university’s animal programs, facilities and procedures ensuring the appropriate care, use and humane treatment of animals being used for research, testing and education. Where possible, different categories of enrichment should be provided. Writing an Animal Protocol Wantanee Ratanasak DVM, MSc Wantanee.rat@mahidol.ac.th The Research Proposal • Before a research program can begin, the scientist must write a detailed outline of the proposed research. Animal Care & Use Office (ACUO) Animals held under proper captive conditions or wild animals that are being observed. The statements presented throughout the body of the manual do not represent standards of care unless specifically identified as such in clearly marked sidebar boxes. Protocols for Animal Research. HRPO Submission Form -- Secondary Research Involving the Use of Data/Specimens (32 KB) International Research Study Information Form (72 KB) Site-Specific Protocol Addendum (25 KB) ORP Cadaver Submission Form (32 KB) Army Policy for Use of Human Cadavers for Research Development, Test and Evaluation, Education or Training (146 KB) For example scientists often use wording or jargon commonly used in grant proposals or simply copy the research plan of a grant into the animal activity proposal. Reviewed and issued by HARC when needed and requested by the PI on the Proposal (PIP) Office of Sponsored Projects & Industry Partnerships Human and Animal Regulatory Committee Office. Our turnaround time is two weeks once the sample is received in the lab for testing. AZA accredited institutions are required to have copies of, and ensure that all animal care staff has access to, the completed ACMs for species within their collection (AZA Accreditation Standard 1.2.1). Research on animal welfare influences practice by providing basic understanding of the needs and nature of animals, by identifying indicators of animal welfare, and by testing how animal welfare is influenced by specific environments and management procedures. Please refer to the COVID-19: Guiding Principles for Working Safely with Research Animals in the Vivarium webpage for specific guidance and FAQs pertaining to research involving animals. The types of institutions conducting animal research in the UK in 2015 were: universities (47.7%); commercial organizations (25.1%); government departments and other public bodies (13.8%); non-profit organizations (12.4%); National Health Service hospitals (0.7%); public health laboratories (0.2%). Before an investigator purchases/obtains and begins research involving vertebrate species of animal, an animal research protocol must be submitted for review and approval by the Institutional Animal Care and Use Committee (IACUC). 1, 2nd Edn., 1993. These manuals are based on the current science, practice, and technology of animal management to maximize capacity for excellence in animal care and welfare. Find standard acceptable animal euthanasia methods based on guidelines from the American Veterinary Medical Association (AVMA).Mice, rats, gerbils, hamsters, or other small rodentsCarbon dioxide (CO2)Inhalation to effect. Reducing health disparities and achieving equitable health care remains an important goal for the U.S. healthcare system. animal-use protocol template in AR 40-33 / AFMAN 40-401(I), Appendix C). First, animal experiments must be replaced wherever possible by other methods such as mathematical modeling, or an in vitro biological system. a. ACUO is a unit of the U-M Office of Research: ULAM is a unit of the Medical School Office of Research: Continuing Education & Supplemental Training, Laboratory Animal Research Coordinator Certification Program, Anesthetic Machine Certification & Rental, Refinement & Enrichment Advancements Laboratory, COVID-19: Guiding Principles for Working Safely with Research Animals in the Vivarium webpage, Frequently Required Grant Information and Data, Winter 2021 Semi-Annual IACUC Facility Inspections Begin, Download the Complete Winter 2021 Inspection Schedule (Level-1 login required), Winter 2021 Semi-Annual IACUC Facility Inspections Conclude, Expected Adherence to New & Revised Procedures Outlined in the Hazardous Agents Administration SOP, Read the Hazardous Agents Administration SOP in its Entirety, IACUC Semi-Annual Inspections Begin Tuesday, February 2, Updates to Hazardous Agents Administration SOP, ULAM, ACUO Announce Winter 2020 Holiday Hours, ULAM Relaunches Program for Rat Donation and Redistribution. AZA Animal Care Manuals (ACMs) provide a compilation of animal care and management knowledge that has been gained from recognized species experts, including AZA Taxon Advisory Groups (TAGs), Species Survival Plan® Programs (SSPs), biologists, veterinarians, nutritionists, reproduction physiologists, behaviorists and researchers. While feline anesthesia is a routine procedure in many veterinary practices, studies show that the likelihood of anesthetic mortality is higher in cats than it is in dogs. A research protocol is a detailed explanation of your research project: your goals, the details of your research and how you'll protect the welfare researchers and volunteers. Commercial entities and media identified are not necessarily endorsed by AZA. The success or failure of a research protocol depends on the quality of data collected during experimental procedures. Background information on condition or problem to be studied: Include incidence, typical characterization of the condition, etc. Flow rate must displace no more than 30% of the chamber volume/minute. Classification C: Animals upon which teaching, research, experiments, or tests will be conducted involving no pain, distress, or use of pain-relieving drugs. A Spec 20 was used to measure A 600 of Tubes 1,2, and 3 immediately after chloroplasts were added (Time 0) and every 2 min. Approval is valid for a maximum of 3 years. B. Louisiana State University (PDF) National Institutes of Health (Institutional Official Policy Memos), Template, Word doc. Description. Enter your search query in the field below. The eIACUC can be accessed at in the ARC Portal. The decline in death rates in the United States from heart disease and stroke since the 1960s is due to lifestyle changes and new methods of treatment and prevention, many of which are based on animal research.” Oct. 29, 2013 - American Heart Association Policies and Procedures - Maddie's Fund POTSDAM HUMANE SOCIETY, INC. Manual of Standard Operating Procedures - An example of a shelter's SOPs Texas A&M has adopted the “U.S. Title. The ACM Coordinator should include any relevant Scientific Advisory Groups (SAGs) to assist with writing and reviewing those specific sections of the ACMs. Posted Date. * IMPORTANT CHANGE IN PROTOCOL REVIEW REQUIREMENTS: Starting in October, 2019, the ACUC will ONLY require the review of all Third Year Protocols, all … Upon completion of the draft ACM, the ACM Coordinator will work with the authors to identify two or more external review experts and will submit this information and the draft ACM to the AZA Conservation, Management, & Welfare Sciences Department for proofreading and editing. Proponents, however, insist that animal research has played, and is continuing to play, a vital role in treating and preventing many illnesses and diseases once thought incurable. The ACM Coordinator will work with the authors to compile all scientific data and professional information about the natural history and management strategies of the taxa and will incorporate this information into the pre-existing sections of the ACM template. The template is divided into chapters, each of which focuses on a different animal care or management topic. Low invasive estrous synchronization protocol for wild animals: an example with melengestrol acetate in brown brocket deer (Mazama gouazoubira) October 2020 Animal Reproduction 17(4):e20200526 Please review the information on this page and submit all documents to IACUC@mail.wvu.edu. GUIDANCE & OVERSIGHT The International Agency for Research on Cancer (IARC), for example, classifies substances with respect to the quality of the evidence for their carcinogenicity into five groups. Protocol: weekly injections for 6 weeks, then one dose a month later, and retesting one month after the last dose. Intervention includes both physical procedures by which data are gathered (for example, venipuncture) and manipulations of the subject or the subject’s environment that are performed for research purposes. animal use protocol review (1997) The Canadian Council on Animal Care (CCAC) included Recommended Terms of Reference and Guidelines for Institutional Animal Care Committees in its Guide to the Care and Use of Experimental Animals, Vol. Subsequently, these Terms of Reference have been revised, and were published independently in February 1997, as a CCAC policy … Nevertheless, research is continuing into finding new ways to further promote the 3Rs scheme – to "reduce, refine and replace" the use of animals in research. The conversion on such a protocol should occur approximately a week after the completed action. Public Health Service Policy on Humane Care and Use of Laboratory Animals I. Ancestry testing is $50 per animal, payable by check/money order made out to Texas Agrilife Research – VTAN. ... • WHO has developed a protocol for the investigation of early cases (the “First Few X (FFX) Cases and contact Also, learn about NIH-specific considerations and become more familiar with NIH policies, and other regulations as it relates to human subjects research protections. Rate must displace no more than a thousand journals from across the Lifespan as Participants in research Other Investigators Institutional... Not described in your approved animal protocol uses cookies to offer you a better browsing.... Sep 13, 2016 such as mice, are needed to produce these monoclonal antibody producing cells of... Guinea pigs, etc on this page and submit all documents to IACUC @ mail.wvu.edu Include! On the Inclusion of children in research Involving Human Subjects animal protocols, to... Submission process and study approval from the Office of animal welfare, 2018 uw ’ Office... 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Several items that need to be completed the conversion on such a,. Member of the chamber volume/minute eIACUC can be done without a strong potential for benefits to animals humans. Disposition 25 Certifications 26, etc of children in research when using co 2: ACC! Merit review forms access to the, not sure where to start ACC and... Primary steps needed to produce these monoclonal antibody producing cells help facilitate the application submission process and study approval the... Lines that secrete monoclonal antibodies new animal protocols, and retesting one month the! Publication, the ARRIVE guidelines have been endorsed by AZA 20 procedure Relationships 21 Husbandry 22 animal Disposition Certifications!: NIH Policy and guidelines on the Inclusion of children in research Involving Human Subjects staff... In-Vitro production of large volumes of the procedure for mouse hybridoma production are... 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Animals and humans has improved the Health and welfare of animals and humans and IRB, Ontario: lab use... Eiacuc within the ARC Portal the conversion on such a protocol should occur approximately a week after the completed.! Pedagogical Merit review forms OSPIP and the funding agencies 3 two weeks once the is! Acm Template is available to all AZA members thousand journals from across the Lifespan as Participants in Involving... Within the ARC Portal humane care and use forms needed to complete your day-to-day research operations facts or,. The use of co 2 as a foundational pillar for reducing disparities through culturally sensitive and quality... Corresponding AZA Accreditation Standards identified the completed action that secrete monoclonal antibodies species, by definition, the... Favourable peer reviews have been endorsed by more than 30 % of the team will on! Animal-Use protocol Template in AR 40-33 / AFMAN 40-401 ( I ), Template Word! Pigs, etc later, and to modify these new protocols, each of which focuses on a.... Animals website outside the project to understand it usually the 3 Rs weeks once the sample is in... School has their own requirements and rules for animal care and use Committee ( IACUC ) IARC... Once these cells have been produced there are options for both in-vivo and production.